Open AccessALCOHOLIC HYALIN‐LIKE BODIES FOUND IN THE PANCREATIC ACINAR CELLS AND NERVE CELLS OF THE BRAIN
Author(s) -
Kojima Kuniji
Publication year - 1975
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1975.tb03258.x
Subject(s) - pathology , staining , nerve cells , eosinophilic , cytoplasm , chemistry , autopsy , electron microscope , ultrastructure , anatomy , biology , medicine , microbiology and biotechnology , biochemistry , physics , optics
The presence of hyalinoid body as an eosinophilic, dendriform to irregularly shaped mass was noted in the cytoplasm of pancreatic acinar cells of 13 among a series of approximately 150 autopsy cases of alcoholism examined. Similar subcellular structures were also demonstrable in nerve cells of the brain in 2 of these cases. The hyalinoid body stained scarlet in phloxine methylene blue preparations and orange‐brown in preparations with the Masson staining method (modified procedure of Gomori), and was revealed to be a fibrillar filamentous mass by electron microscopy. These characteristics suggest its marked resemblance to alcoholic hyalin in liver cells.