Open AccessRETICULOSARCOMATOSIS ORIGINATING FROM SKIN—A CLINICOPATHOLOGICAL STUDY
Author(s) -
Okayasu Isao,
Okayasu Noriko,
Mori Wataru,
Miyazaki Kazuhiro,
Matsubara Sho
Publication year - 1975
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1975.tb00857.x
Subject(s) - pathology , infiltration (hvac) , lymph , autopsy , medicine , biopsy , lymphatic system , thermodynamics , physics
The case is that of a 65 year‐old male with reticulosarcomatosis originating from the skin. There were multiple tumors composed of reticulum cells located only in the skin, particularly around the large joints. The entire course of illness was three years and five months, during which period regression by irradiation, recurrence, or new forma tion of tumors were repeatedly seen. At the end systemic tumor spread not only of the skin but also in various visceral organs including lymph nodes occurred. From histological and electron microscopic examinations repeatedly performed with biopsy materials, and finally with autopsy materials it was ascertained that the tumor cells had become smaller in size with less lymphoid cell infiltration at the terminal stage.