Open AccessAN AUTOPSY CASE OF NIEMANN‐PICK DISEASE
Author(s) -
Kawai Kioko,
Tsuchiyama Hideo,
Tabata Kimiko
Publication year - 1973
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1973.tb02779.x
Subject(s) - niemann–pick disease , autopsy , pathology , medicine , disease
An autopsy case of Niemann‐Pick disease whichμ was characterized by hepatosplenomegaly and lymphadenopathy is reported. On microscopic examination, numerous foamy cells were observed in the liver, spleen, kidneys, bone marrow, lungs, thymus, intestine and general lymph nodes. These cells were generally negative for periodic acid‐Schiff (PAS) stain and positive for staining of phospholipid. Based upon the morphologic characteristics of Niemann‐Pick disease, its relation to other lipidosis is discussed.