Open AccessAN AUTOPSY CASE OF RADIATION MYELOPATHY
Author(s) -
Ishida Yooichi,
Hashiba Yukiko,
Kanda Hiroshi,
Tanaka Takashi,
Niibe Hideo
Publication year - 1973
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1973.tb00800.x
Subject(s) - medicine , autopsy , myelitis , myelopathy , spinal cord , radiation therapy , cervical lymph nodes , pathology , parenchyma , radiology , cancer , metastasis , psychiatry
An autopsy case of radiation myelopathy Is described in a 24‐year‐old woman, who had developed signs of progressive myelitis following repeated courses of radiation therapy for a lymphoepithelioma of the nasopharynx with metastases to the cervical lymph nodes. Histopathologic studies disclosed an extensive area of necrosis in sections of the upper cervical spinal cord coextensive with an area of irradiation. Vascular changes were prominent and a glial reaction was sparse. It is suggested that a vasculo‐circulatory factor plays an important role in the production of the parenchymal lesion.