Open AccessMORPHOLOGY OF EXPERIMENTAL CHORIONIC TUMORS IN RATS
Author(s) -
Miyamoto Makoto,
Nilsuwarn Naiyana,
Angsubhakorn Subhkij
Publication year - 1972
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1972.tb00745.x
Subject(s) - dmba , gross morphology , pathology , carcinogen , gross examination , placenta , medicine , biology , cancer , anatomy , pregnancy , carcinogenesis , fetus , biochemistry , genetics
Four additional chorionic tumors have been obtained by the same method as previously reported1 using 4‐NQO and 7,12‐DMBA as carcinogens. It was observed that high dosage of DMBA was quite effective in inducing chorionic tumors in rats. Gross and histological appearance of the tumor resembled that of normal placenta in rats. Part of the tumor has been transplanted and is now under observation.