Open AccessCHRONIC MYELOGENOUS LEUKEMIA IN RATS FED 2,7‐DIACETYLAMINOFLUORENE
Author(s) -
Takayama Shojiro,
Yamada Takashi,
Kamata Shoji
Publication year - 1972
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1972.tb00743.x
Subject(s) - chronic myelogenous leukemia , leukemia , medicine , pathology
We originally attempted to induce a gastric carcinoma in 327 female rats by the oral administration of 2,7‐dlacetylaminofluorene. Gastric carcinoma, however, did not appear, while leukemia was found In 31 cases (9.5%). Chronic myelogenous leukemia was encountered in 29 cases (8.9%). This leukemia in rats morphologically resembles chronic myelogenous leukemia in man.