Open AccessSURFACE MEMBRANE OF LYMPHOCYTES
Author(s) -
Watanabe Shaw,
Mikata Atuso,
Tadakuma Takushi,
Niki Rikio,
Kageyama Keizo
Publication year - 1971
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1971.tb00139.x
Subject(s) - pathology , medicine
The quantitative relationship of lymphoid antigenic determinants between lymphoid cells and antilymphocytic globulin or antithymocytic globulin was studied. 131 I‐ALG or ATG were sensitive enouth to detect adsorption on cytomembrane, although nonspecific adsorption occurred in a few percent and this was negligible in case of using purified ALG or ATG. The existence of several kind of lymphoid antigens was proved, viz. common lymphoid, lymphocyte‐specific and thymocyte‐specific antigen. It was also suggested that thymocytes had a fewer kind of antigen determinants but the total number of radicals was the same as lymphocytes, and that each cell surface had several thousands of molecules which acted as lymphoid antigen determinant.