Open AccessAN ELECTRON MICROSCOPIC STUDY OF ERYTHROLEUKEMIA, WITH SPECIAL REFERENCE TO THE STRUCTURE OF ERYTHROBLASTS
Author(s) -
Kamiyama Ryuichi
Publication year - 1971
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1971.tb00121.x
Subject(s) - erythroblast , nucleolus , cytoplasm , pathology , organelle , electron microscope , bone marrow , nucleus , iliac crest , biology , microbiology and biotechnology , chemistry , anatomy , medicine , haematopoiesis , physics , stem cell , optics
The bone marrow taken by either sternal or iliac crest aspiration of four cases of erythroleukemia was studied electron microscopically to reveal the following results. The erythroblast in erythroleukemia showed abnormalities both in the nucleus and cytoplasmic organelles, especially in the nucleolus and mitochondria. In two cases of erythroleukemia, unclassifiable blastic cells which were usually located near the sinus, were observed. Generally, the erythroblast has a few, high electron dense granules having no internal structure.