Open AccessRUBINSTEIN‐TAYBI'S SYNDROME—A CASE REPORT
Author(s) -
Fukunaga Noboru,
Suda Sekito,
Ebihara Yoshiroh,
Laovoravit Niphon,
Laovoravit Mani
Publication year - 1969
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1969.tb00092.x
Subject(s) - rubinstein–taybi syndrome , autopsy , hypoplasia , medicine , pathology , central nervous system , anatomy , dermatology
An autopsy case of Rubinstein‐Taybi's syndrome is described. Since the mental retardation is considered to be a part of the syndrome, central nervous system was carefully examined, illustrating a moderate degree of the cerebral cortical and callosal hypoplasia and diffusely distrlbuted neuronal anoxic changes possibly associated with cardio‐pulmonary insufficiency. As far as the pathognomony of the facio‐osseal deformities, no convinciable causative factors have been obtained.