Open AccessAN ULTRASTRUCTURAL STUDY OF HUMAN JUXTAGLOMERULAR CELLS
Author(s) -
Ishii Yoshifumi,
Fujimoto Teruo
Publication year - 1968
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1968.tb00073.x
Subject(s) - juxtaglomerular apparatus , ultrastructure , pathology , biology , medicine , microbiology and biotechnology , renin–angiotensin system , endocrinology , blood pressure
An electron microscopic investigation was made on the Juxtaglomerular cells (JC) of human renal glomeruli. This study corroborates the myoepithelioid appearance of JC situated in the wall of the afferent arteriole. These cells contain secretion granules as well as fibrillar bundles similar to myofilaments of the smooth muscle cells, while JC located farthest from the afferent arteriole lack them. In addition, a transitional form from agranular to granular JC is noted. It is presumed that (1) JC have a potency of a two‐way differentiation (muscular and endocrine), and (2) granular JC are derived from agranular JC. The existence of several types of intercellular Junctions and the occurrence of cilia in human JC have also been demonstrated in the present study.