Open AccessTHE ROLE OF VIRUS IN THE GROWTH OF VIRAL LEUKEMIA CELLS
Author(s) -
Kobayashi Hiroshi,
Hosokawa Masuo,
Takeichi Noritoshi
Publication year - 1968
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1968.tb00064.x
Subject(s) - virus , leukemia , virology , biology , virus diseases , tumor virus , pathology , cancer research , immunology , medicine , cancer , carcinogenesis , genetics
It is said that ‘Neoplasms can proliferate autonomously without continuation of stimuli’. This is true but also true to say that some virus‐induced tumors are necessary to maintain the causative virus and they can not proliferate without the continuation of virus. The authors have carried out experiments in order to elucidate the role played by viruses in the maintenance of proliferation of virus‐induced neoplastic cells. The leukemia cells employed by the authors were designated as ‘Friend tumors’, which were originated from Friend virus‐induced neoplastic lesions and have been serially transplanted in mice and rats.