Open AccessAN AUTOPSY CASE OF ISLET‐CELL CARCINOMA WITH CUSHING'S SYNDROME *
Author(s) -
Uei Yoshio,
Kim U,
Itatsu Yoshiaki
Publication year - 1968
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1968.tb00058.x
Subject(s) - autopsy , pathology , islet , medicine , diabetes mellitus , endocrinology
A case of islet‐cell carcinoma with Cushing's syndrome observed in a 9y‐ear‐old Japanese girl who expired 8 months after the onset of symptoms was presented. ACTH activity was demonstrated in the tumor by means of biological and immunological methods. Autopsy findings were consistent with the Cushing's syndrome except for a peculiar type of hyaline change of the pituitary cell, which was briefly discussed from the view point of corticotrophogenesis. Cases of islet‐cell tumor associated with Cushing's syndrome so far reported in the world literature were reviewed. ACTA PATH. JAP. 18: 333–343, 1968.