
PATHOGENESIS OF SO‐CALLED CONGENITAL ANEURYSMS OF THE BRAIN *,**
Author(s) -
Sugai Masayoshi,
Shoji Munesuke
Publication year - 1968
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1968.tb00044.x
Subject(s) - aneurysm , subarachnoid hemorrhage , pathogenesis , circle of willis , medicine , cerebral arteries , anatomy , pathology , radiology , surgery
The major and minute aneurysms of the cerebral arteries were investigated by means of morphological and statistical examination methods in a series consisting of 100 cases of subarachnoid hemorrhage, 28 cases of cerebral hemorrhage, and 54 cases of other diseases. It was found that the VP of Rotter et al. first develops at the proximal part of the arterial fork and its distal part distends secondarily to the VP‐formation resulting in the formation of a minute aneurysm. Thereafter with the lapse of age, the minute aneurysm becomes increased in size in addition to arteriosclerotic changes and the saccular or so‐called congenital aneurysm is formed. During this process congenital or acquired factors promoting the aneurysm‐formation are also superimposed corporately with each other. As local factors circle anomalies of Willis, thinness and development of VP of cerebral arteries, retrograde or complicated branching, widening of the fork angle at bifurcation, etc. and as bodily systemic factor hypertension with aging process are mentioned, and some of them may also act favorably for the development of VP. ACTA PATH. JAP. 18: 139–160, 1968.