Open AccessCORONARY SCLEROSIS
Author(s) -
Otsu Syoichi
Publication year - 1968
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1968.tb00043.x
Subject(s) - internal elastic lamina , medicine , thickening , lumen (anatomy) , eccentric , coronary arteries , fibrosis , pathology , stenosis , cardiology , anatomy , artery , chemistry , physics , quantum mechanics , polymer science
The human coronary arteries were examined both histologically and histometrically. The materials were obtained from autopsies of every decade of age, which consisted of 13 cases with and 41 without hypertension. It was revealed that diffuse thickening of the intima in coronary arterial system develops earlier in age and more frequently than in the other, and the degeneration as well as fragmentation of the internal elastic lamina are prone to become apparent with aging. At the same time the internal elastic lamina and the media seem to be extended in many cases, resulting in thinning of the media and masking of its fibrosis. Coronary sclerosis was more evident at the onset of its muscular type segment, being different from sclerosis in other arterial systems, and was morphologically divided into two types; eccentric and diffuse sclerosis. Although the former type causing eccentric stenosis of the lumen was more frequently encountered, it is noticeable that the latter showing marked pipe‐stem‐like stenosis was more often found in the coronary arterial system than in the others. This type seems to be formed on the basis of diffuse thickening of the intima. ACTA PATH. JAP. 18 : 123–135, 1968.