Open AccessA n A utopsy C ase of C hronic R heumatic C arditis with M yocardial A schoff B odies
Author(s) -
Isomura Nobuyuki,
Hara Hiroshi,
Kubota Itsuro
Publication year - 1957
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1957.tb03003.x
Subject(s) - connective tissue , pathology , autopsy , calcification , infiltration (hvac) , myocyte , anatomy , chemistry , contraction (grammar) , medicine , physics , thermodynamics
Summary An autopsy case of chronic rheumatic carditis is described. The patient was a woman aged 32 years and the duration of the disease was more than eight years. At autopsy, the heart showed typical mitral stenosis with verrucous scarring, calcification and contraction of the valve. Areas of degenerating muscle cells and proliferation of the interstitial connective tissue, partly with perivascular infiltration, were seen throughout the myocardium, and heart muscles showed narrowing and fragmentation. There was fibrinoid degeneration of the wall in small coronary vessels. Numerous Aschoff bodies of various structures were found mostly in the proliferated interstitial connective tissue, between damaged muscle bundles and adjacent to the small coronary vessels of the myocardium. A small number of Aschoff bodies were situated in the subendocardial tissue in which there was no muscle.