
B one C hange in the F etus F ollowing T oxemia of the P regnant M other
Author(s) -
Ohkawa Kimiyasu
Publication year - 1951
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1951.tb00730.x
Subject(s) - calcification , bone marrow , ossification , cartilage , pathology , anatomy , chemistry , medicine
SUMMARY Bone changes of the fetus following toxemia of pregnant mother, is studied. This study shows: (1) Slight shortening of the proliferative cartilage zone. (2) Evident shortening of the zone of ossification and chondro‐osseous trabeculae that are arranged and shaped irregularly, and the irregular dilatation of the primary marrow. (3) The primary marrow capillaries seem to have the pathologic hyperfunction to invade the cartilage. (4) The dilatation of marrow, and the narrow trabeculae. (5) The thin cortex and the dilatation of the canals of H avers . These changes occur in proportion to the extent of clinical symptoms at the time of labour. The more serious the clinical symptoms at the time of labour are, the more evident these changes become. (6) The increase of osteoblasts: some show atrophic changes, others necrotic changes. (7) The decreasing of calcification stained by hematoxylin. (8) The hemorrhage in the marrow. These changes are in proportion to the course of clinical symptoms and not specific to toxemia, but have only a difference of extent. The irregular arrangement of the capillaries invading the cartilage is specific in toxemia.