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Distress due to lithium‐induced polyuria: Exploratory study
Author(s) -
Pradhan Basant K.,
Chakrabarti Subho,
Irpati Anand S.,
Bhardwaj Rahul
Publication year - 2011
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/j.1440-1819.2011.02214.x
Subject(s) - polyuria , medicine , lithium (medication) , distress , urine , urology , endocrinology , clinical psychology , diabetes mellitus
Lithium‐induced polyuria, although common, often goes unrecognized. The purpose of the present study was therefore to investigate the complaints of polyuria, and distress and functional impairment associated with polyuria, in 56 patients with bipolar disorder on long‐term lithium treatment. All participants underwent 24‐h urine collection, and renal function tests. Polyuria (24‐h urine volume > 3 L) was found in 70% of subjects. Unless directly enquired about, polyuria was underreported. Impairment in work and daily routine due to increased urine output/frequency was associated with 24‐h urine volumes. Polyuria is a highly prevalent, distressing and impairing side‐effect of long‐term lithium treatment, requiring due attention.