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Hyperperfusion in primary somatosensory region related to somatic hallucination in the elderly
Author(s) -
Nemoto Kiyotaka,
Mizukami Katsuyoshi,
Hori Takafumi,
Tachikawa Hirokazu,
Ota Miho,
Takeda Tohoru,
Ohnishi Takashi,
Matsuda Hiroshi,
Asada Takashi
Publication year - 2010
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/j.1440-1819.2010.02101.x
Subject(s) - somatosensory system , cerebral blood flow , perfusion scanning , medicine , perfusion , population , audiology , psychology , neuroscience , anesthesia , psychiatry , radiology , environmental health
Aim: The purpose of the present study was to investigate the regional cerebral blood flow (rCBF) of patients with delusional disorder, somatic type (DDST) exhibiting somatic hallucination. Methods: Five patients diagnosed with DDST, as well as 20 control subjects, were examined. All subjects underwent technetium‐99 m ethyl cysteinate dimer brain perfusion single‐photon emission computed tomography. Statistical analysis was performed with SPM5, using a two‐sample t ‐test model to test the regional population effect on rCBF. Results: Patients with DDST had a significant increase in perfusion in the left post‐central gyrus and the right paracentral lobule, both of which are involved in somatic sensory processing. Conclusion: Somatic hallucination might be associated with increased perfusion in the primary somatosensory regions.