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Relationship of psychopathological symptoms and cognitive function to subjective quality of life in patients with chronic schizophrenia
Author(s) -
Tomida Kenji,
Takahashi Nagahide,
Saito Shinichi,
Maeno Nobuhisa,
Iwamoto Kunihiro,
Yoshida Keizo,
Kimura Hiroyuki,
Iidaka Tetsuya,
Ozaki Norio
Publication year - 2010
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/j.1440-1819.2009.02033.x
Subject(s) - psychopathology , positive and negative syndrome scale , schizophrenia (object oriented programming) , wisconsin card sorting test , anxiety , quality of life (healthcare) , psychology , clinical psychology , psychosocial , cognition , hospital anxiety and depression scale , psychiatry , depression (economics) , psychosis , neuropsychology , psychotherapist , economics , macroeconomics
Aims:  The purpose of the present study was to examine the extent of the effects of psychopathological symptoms and cognitive function on quality of life (QOL) in patients with chronic schizophrenia. Methods:  Data were obtained using the Japanese Schizophrenia Quality of Life Scale (JSQLS), Positive and Negative Syndrome Scale (PANSS), Wisconsin Card‐Sorting Test (WCST) Keio version, and Continuous Performance Test (CPT) for 52 schizophrenia patients. Results:  Stepwise regression analysis showed that PANSS depression/anxiety factors predicted JSQLS psychosocial conditions and motivation/energy, and that WCST Categories Achieved predicted JSQLS symptoms/side‐effects. Conclusions:  Psychopathological symptoms and cognitive function affect subjective QOL in patients with schizophrenia. If the final goal is treatment that improves QOL in a manner that patients themselves are aware of, clinicians probably need to consider a treatment strategy that improves depression/anxiety symptom.

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