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Four cases of venous thromboembolism associated with olanzapine
Author(s) -
Maly Radovan,
Masopust Jiri,
Hosak Ladislav,
Urban Ales
Publication year - 2009
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/j.1440-1819.2008.01899.x
Subject(s) - olanzapine , venous thromboembolism , medicine , antipsychotic , cohort , psychiatry , cohort study , intensive care medicine , pediatrics , schizophrenia (object oriented programming) , thrombosis
Aims: Psychiatric disorders and treatment with conventional antipsychotic medications have been associated with venous thromboembolism, but only a few data on recent antipsychotics such as olanzapine are available. Methods: We describe four subjects treated with olanzapine who developed venous thromboembolism, and were hospitalized at the University Hospital in Hradec Kralove during the period 2004–2006. Results: We found a combination of several clinical and laboratory risk factors in our patients. Conclusions: A cohort study or case–control studies are needed to better elucidate the possible role of olanzapine in etiopathogenesis of venous thromboembolism.