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Dexamethasone suppression test in borderline personality disorder: Impact of PTSD symptoms
Author(s) -
WINGENFELD KATJA,
HILL ANDREAS,
ADAM BETTINA,
DRIESSEN MARTIN
Publication year - 2007
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/j.1440-1819.2007.01728.x
Subject(s) - borderline personality disorder , dexamethasone suppression test , dexamethasone , psychology , clinical psychology , medicine , psychiatry , posttraumatic stress
The purpose of the present study was to investigate the impact of post‐traumatic stress disorder (PTSD) symptoms on hypothalamic–pituitary–adrenal axis feedback regulation in 18 female patients with borderline personality disorder (BPD) and 21 healthy controls. Reduced feedback sensitivity was found in BPD patients with a low number of PTSD symptoms, while findings in the BPD group with a high number of PTSD symptoms did not differ from those in controls. The results suggest a hypo‐suppression in the dexamethasone suppression test in BPD with few PTSD symptoms.