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Serum brain‐derived neurotrophic factor levels in conversion disorder: Comparative study with depression
Author(s) -
DEVECI ARTUNER,
AYDEMIR OMER,
TASKIN ORYAL,
TANELI FATMA,
ESENDANACI AYSEN
Publication year - 2007
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/j.1440-1819.2007.01710.x
Subject(s) - major depressive disorder , brain derived neurotrophic factor , depression (economics) , neurotrophic factors , pathophysiology , medicine , psychology , psychiatry , endocrinology , cognition , receptor , macroeconomics , economics
The aim of the present study was to compare serum brain‐derived neurotrophic factor (BDNF) levels of patients with major depressive disorder (MDD) and conversion disorder (CD). Serum BDNF levels were measured in the following three groups: 15 CD patients without any comorbid diagnosis of psychiatric disorder, 24 patients with MDD, and 26 healthy subjects without any psychiatric diagnosis or psychiatric treatment. The serum BDNF level of the healthy control group (31.4 ± 8.8 ng/mL) was statistically higher than the level of the MDD group (21.2 ± 11.3 ng/mL) and the CD group (24.3 ± 9.0 ng/mL; P = 0.008). This suggests that BDNF level may play a similar role in the pathophysiology of MDD and CD.