Premium
Long‐term seizure outcome following resective surgery at National Epilepsy Center in Shizuoka, Japan
Author(s) -
MIHARA TADAHIRO,
MATSUDA KAZUMI,
TOTTORI TAKAYASU,
OTSUBO TOSHIAKI,
BABA KOICHI,
NISHIBAYASHI HIROKI,
INOUE YUHSHI,
YAGI KAZUICHI
Publication year - 2004
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/j.1440-1819.2004.01244_6.x
Subject(s) - medicine , temporal lobe , refractory (planetary science) , epilepsy , surgery , resection , lesion , single center , epilepsy surgery , lobe , complex partial seizures , stage (stratigraphy) , psychiatry , pathology , physics , astrobiology , paleontology , biology
We analyzed the seizure outcome of 357 patients who were followed for at least 2 years after resective surgeries; 282 underwent temporal lobe resection and 75 had extratemporal lobe resection. This study confirmed that resective surgery provides sustained, positive benefits with a high seizure‐free rate of nearly 80% for most medically refractory patients. In patients with no MRI‐detectable lesion who underwent extratemporal lobe resection, however, Engel's class I–II (seizure‐free or rare seizures) was achieved in less than 50% of patients. High‐resolution MRI should be performed at the early stage of disease in all patients with partial epilepsies. The findings would certainly urge clinicians to actively select surgical intervention.