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Non‐existence of a positive correlation between urinary levels of α 1 ‐microglobulin and ulinastatin in patients with Parkinson's disease
Author(s) -
INAGAKI TAKUJI,
SHIKIMI TADAHIRO,
MATSUBARA KAZUO,
KOBAYASHI SHOUTAI,
ISHINO HIROSHI,
OKUNISHI HIDEKI,
TAKAORI SHUJI
Publication year - 1996
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/j.1440-1819.1996.tb02747.x
Subject(s) - ulinastatin , beta 2 microglobulin , parkinson's disease , dementia , correlation , medicine , disease , mood , urinary system , degenerative disease , psychology , gastroenterology , central nervous system disease , positive correlation , psychiatry , geometry , mathematics
Urinary levels of a,‐microglobulin (αlM) and of ulinastatin (UT) and the αlM/UT ratio did not differ significantly between age‐matched controls and patients with Parkinson's disease, and among subdivided groups based on Yahr's stages in Parkinson's disease. Furthermore, these indexes did not correlate with Yahr's stages. Although αlM and UT levels did not correlate in patients with Parkinson's disease, a positive correlation was observed in the control group. The non‐existence of a positive correlation between αlM and UT levels distinguishes Parkinson's disease from other neuropsychiatric diseases such as dementia (Alzheimer‐type and vascular dementia), schizophrenia and mood disorder.