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A multicenter study of sleep‐wake rhythm disorders: Therapeutic effects of vitamin B 12 , bright light therapy, chronotherapy and hypnotics
Author(s) -
YAMADERA HIROSHI,
TAKAHASHI KIYOHISA,
OKAWA MASAKO
Publication year - 1996
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/j.1440-1819.1996.tb02743.x
Subject(s) - chronotherapy (sleep phase) , medicine , rhythm , circadian rhythm , delayed sleep phase , sleep (system call) , light therapy , sleep disorder , anesthesia , audiology , insomnia , psychiatry , computer science , operating system
One hundred and six subjects with primary sleep‐wake rhythm disorders [13 non‐24 hour sleep‐wake syndrome (non‐24), 76 delayed sleep phase syndrome (DSPS), 11 irregular sleep‐wake pattern (irregular) and six long sleepers] were treated with vitamin B 12 , bright light, chronotherapy and/or hypnotics. These therapies caused moderate or remarkable improvement in 32% of the non‐24, 42% of DSPS, 45% of irregular and 67% of long sleepers. A lack of adequate sleep, unpleasant feelings at waking and daytime drowsiness were also improved in DSPS.

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