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Higher cerebral dysfunction in a case with atypical multiple sclerosis with concentric lesions
Author(s) -
MORIOKA CHIKAKO,
NAMETA KEN,
KOMATSU YOICHI,
TSUTIO TAKEHIKO,
KONDO HIDEKI
Publication year - 1996
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/j.1440-1819.1996.tb01661.x
Subject(s) - concentric , multiple sclerosis , medicine , neuroscience , clinical neurology , psychology , physical medicine and rehabilitation , psychiatry , geometry , mathematics
A patient with atypical multiple sclerosis (MS) with clear concentric structure was studied using high field magnetic resonance imaging (MRI). This case was considered to be Balo's concentric sclerosis. Magnetic resonance imaging showed diffuse multiple concentric demyelinating lesions in the bilateral centrum semiovales, which finally regressed with the necrotic lesions remaining when the patient was discharged. During his clinical course, he showed some higher cerebral dysfunctions, such as memory disturbance, constructual apraxia and acalculia. He was treated with glycerin, prednisone and rehabilitation; all of which were effective in his recovery. Over a 4 month period, the patient recoveredclinically, but some intellectual impairment remained.