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Peripheral Neuropathy Associated with Ulcerative Colitis
Author(s) -
Kanzaki Akihiro,
Yabuki Seiso,
Takasaki Motohiro,
Ueno Kunio,
Yorimitsu Yukio,
Shirabe Teruo
Publication year - 1994
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/j.1440-1819.1994.tb03086.x
Subject(s) - peripheral neuropathy , medicine , ulcerative colitis , sural nerve , gastroenterology , colonoscopy , sensory neuropathy , colitis , peripheral , surgery , disease , endocrinology , cancer , colorectal cancer , diabetes mellitus
This is a report of two cases of peripheral neuropathy associated with ulcerative colitis (UC). Patient 1 developed asymmetric neuropathy two weeks after the onset of UC. Subsequent neurological improvement paralleled the improvement in the active UC as revealed by colonoscopy. Patient 2 exhibited sensory ataxic neuropathy with deposits of IgG and Λ chain in the sural nerve. Both patients showed axonal neuropathy, and corticosteroid therapy improved the neurological symptoms. These types of neuropathy have not previously been reported in association with UC.