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Three‐Dimensional Surface Display Using 123 I‐IMP in a Case of Motor Neuron Disease with Dementia
Author(s) -
Okuda Bungo,
Kawabata Keita,
Tachibana Hisao,
Sugita Minoru,
Fukuchi Minoru
Publication year - 1993
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/j.1440-1819.1993.tb01805.x
Subject(s) - dementia , lesion , neuroscience , frontal cortex , motor cortex , cortex (anatomy) , motor system , frontal lobe , sensory system , medicine , disease , psychology , pathology , stimulation
A case of motor neuron disease with dementia is presented. A brain CT showed atrophic changes mainly in the left frontal cortex, and 123 I‐IMP SPECT disclosed a decrease in 123 I‐IMP uptake in the frontal regions. To distinguish a subregion related to dementia from that related to motor system disorders, a three‐dimensional surface display with 123 I‐IMP was reconstructed. The imaging method clearly demonstrated cortical hypoperfusion in the inferomedial frontal cortex and the motor‐sensory cortex. These findings suggest that dementia may be due to the former lesion and motor system disorders due to the latter lesion, respectively.