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Shortening of N1 and P3 Latencies in Event‐Related Potentials Observed Coincidentally with Clinical Improvement during Nootropic Medication in a Demented Patient: Specific Effect of Nicergoline
Author(s) -
Fukuda Masato,
Hiramatsu KenIchi,
Honda Makoto,
Niwa ShinIchi,
Sasaki Tsukasa,
Hata Akinobu,
Nakagome Kazuyuki,
Iwanami Akira,
Honda Hideo,
Hayashida Seiki,
Itoh Kenji
Publication year - 1992
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/j.1440-1819.1992.tb02861.x
Subject(s) - latency (audio) , event related potential , dementia , nootropic , psychology , cognition , medicine , audiology , neuroscience , computer science , telecommunications , disease
Event‐related potentials, measured eight times in a patient in the early stages of dementia, demonstrated that clinical symptoms, especially loss of motivation, improved coincidentally with a shortening of reaction time, N1 latency, and P3 latency during nicergoline medication among three nootropics prescribed. Such a longitudinal study design was considered to be useful for quantifying and objectively comparing effects of various nootropics non‐invasively.

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