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Animal Models: Behavior and EEG Changes of Unanesthetized Cats after Kainic Acid Injection into Unilateral Caudate Nucleus
Author(s) -
Takano Katsunobu,
Tanaka Tatsuya,
Fujita Tsutomu,
Yonemasu Yukichi
Publication year - 1992
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/j.1440-1819.1992.tb00927.x
Subject(s) - caudate nucleus , kainic acid , cats , microinjection , neuroscience , epilepsy , electroencephalography , nucleus , psychology , medicine , anesthesia , receptor , glutamate receptor
Summary 1. The microinjection of KA into the unilateral caudate nucleus induces secondarily generalized seizure. 2. The caudate nucleus considered to be one of the important relay structures in the generalization of epilepsy. 3. In this model of caudate nucleus epilepsy, cats did not show spontaneous seizure or choreic movement in the chronic stage.