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Serial Changes of SPECT in Periodic Synchronous Discharges in a Case with Creutzfeldt‐Jakab Disease
Author(s) -
Kan Rumiko,
Takahashi Yukio,
Sato Koji,
Watabe Manabu,
Tago Hisao,
Yashima Yuko,
Kumashiro Hisashi
Publication year - 1992
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/j.1440-1819.1992.tb00831.x
Subject(s) - cerebrum , electroencephalography , third stage , cerebellum , stage (stratigraphy) , brainstem , pathological , third person , cerebral blood flow , medicine , psychology , neuroscience , anesthesia , pathology , central nervous system , physics , biology , training (meteorology) , paleontology , meteorology , psychoanalysis
We conducted serial EEG and SPECT studies on one female with Creutz‐feldt‐Jakob disease (CJD). In an analysis of EEG, a periodic synclmnons discharge WD) was observed in the middle of the third stage (terminal stage) of Bernonlli's classification. “he frequency of PSD was the highest at the begiMing of the third stage, followed by a gradual decrease and disappeared at the end of the third stage. In the middle of the third stage, SPECT disclosed blood flow differences between the cerebrum and other regions (the cerebellum amd the brainstem), while no such difference was observed by SPECT at the end of the third stage. It was snggested that the appearance of PSD requires the presence of a pathological change in the cerebrum precedent to other regions.