Premium
Sex Concordance in Proband‐Relative Pairs with Schizophrenia
Author(s) -
Shimizu Akinori,
Noda Makiko,
Kurachi Masayoshi,
Yamaguchi Nariyoshi,
Torii Hosaku,
Isaki Kiminori
Publication year - 1991
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/j.1440-1819.1991.tb01181.x
Subject(s) - proband , concordance , schizophrenia (object oriented programming) , psychosis , psychology , psychiatry , medicine , genetics , biology , gene , mutation
Sex concordance rates were investigated in 278 schizophrenic probands, who had at least one first‐degree relative with schizophrenia, in order to find out whether the illness affects the same sex more often than the opposite sex when two close relatives become ill. No such unusual concordance rates were found in proband‐relative pairs with schizophrenia. When 118 of the 278 probands were examined who had at least one parent with schizophrenia, the morbidity risk for schizophrenia in siblings of the same sex as the schizophrenic probands was significantly higher than that found in siblings of the sex opposite that of schizophrenic probands.