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Carmofur‐Induced Organic Mental Disorders
Author(s) -
Suzuki Toshihito,
Koizumi Junzo,
Uchida Kaoru,
Shiraishi Hiroyasu,
Hori Masashi
Publication year - 1990
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/j.1440-1819.1990.tb01650.x
Subject(s) - euphoriant , frontal lobe , lateral ventricles , white matter , psychology , mental state , organic mental disorders , personality disorders , personality , organic brain syndrome , audiology , psychiatry , neuroscience , medicine , magnetic resonance imaging , radiology , psychoanalysis , delirium
Summary: Organic mental disorder was observed in a 29‐year‐old female in the prognostic period after the onset of carniofur‐induced lenkoencephalopathy. Symptoms such as euphoria, emotional lability and puerile attitude noted in the patient were diagnosed as organic personality syndrome according to the criteria defined in the DSM‐HI‐R. It is referred to as a frontal lobe syndrome. Brain CT revealed a periventricular low density area in the frontal white matter and moderate dilatation of the lateral ventricles especially at the bilateral anterior horns. Consequently, carmofur‐induced leukoencepha‐lopathy may uncommonly result in organic personality syndrome in the residual state. It may be attributed to the structural damage to the frontal lobe.