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REM Sleep without Muscle Atonia (Stage 1‐REM) and Its Relation to Delirious Behavior during Sleep in Patients with Degenerative Diseases Involving the Brain Stem
Author(s) -
Shimizu Tetsuo,
Inami Yasushi,
Sugita Yoshio,
Iijima Susami,
Teshima Yoshio,
Matsuo Ryunosuke,
Yasoshima Aki,
Egawa Isao,
Okawa Masako,
Tashiro Tetsuo,
Hishikawa Yasuo
Publication year - 1990
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/j.1440-1819.1990.tb01645.x
Subject(s) - rem sleep behavior disorder , rapid eye movement sleep , non rapid eye movement sleep , slow wave sleep , k complex , psychology , sleep (system call) , electroencephalography , sleep stages , medicine , neuroscience , polysomnography , computer science , operating system
Nocturnal sleep was examined in 12 patients with degenerative diseases involving the brain stem and in 2 patients with late cerebellar cortical atrophy (LCCA). A peculiar sleep state, characterized by the concomitant appearance of a low‐voltage mixed frequency EEG, rapid eye movements (REMs) and tonic EMG in mental muscles, repeatedly appeared during nocturnal sleep in all of the 12 patients with degenerative diseases involving the brain stem and it was called stage 1‐REM after Tachibana et al. 32 In 8 of the 12 patients, delirious or oneiric behavior appeared during, or soon after, the episodes of stage 1‐REM. Inner experiences reported by one of the subjects well corresponded to his behavior during the episode of stage 1‐REM. Stage 1‐REM was not observed during nocturnal sleep of the patients with LCCA. These results indicate that a degenerative lesion in the brain stem induced stage 1‐REM and delirious behavior during nocturnal sleep through abolishing muscle atonia of REM sleep and causing dissociation of the functional components characterizing REM sleep.