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Mental Disorders Induced by Carbamazepine
Author(s) -
Mizukami Katsuyoshi,
Naito Yutaka,
Yoshida Motoaki,
Nakanishi Takao,
Koizumi Junzo
Publication year - 1990
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/j.1440-1819.1990.tb00441.x
Subject(s) - carbamazepine , hypomania , medicine , discontinuation , psychiatry , anesthesia , trigeminal neuralgia , psychology , mania , epilepsy , bipolar disorder , mood
We present here a case with various physical and neuropsychiatry symptoms caused by the administration of carbamazepine. The patient suffering from right opthal‐mic neuralgia showed fever, eczema, erythema, lymphoadenopathy, eosinophilia, vomiting, headache, dizziness, nystagmus, and various mental disorders which consisted of emotional instability, personality change, delusions of reference and persecution, depressive state, and hyperventilation syndrome during the administration of carbamazepine. The physical symptoms in the present case were conformable to the side effect of carbamazepine. The mental disorders appeared in a few days from the start of carbamazepine administration and disappeared after the discontinuation of the administration of this drug without antipsychotic therapy and have never relapsed until now. The mental disorders and the physical symptoms were in parallel with their clinical course. This kind of mental disorders induced by carbamazepine has not yet been reported.