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Meige's Syndrome during Long‐Term Neuroleptic Treatment
Author(s) -
Kurata Kouichi,
Yuasa Satoru,
Kazukawa Satoru,
Kurachi Masayoshi,
Fukuda Tsutomu
Publication year - 1989
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/j.1440-1819.1989.tb03097.x
Subject(s) - term (time) , psychology , psychiatry , medicine , physics , quantum mechanics
Two patients developed difficulties in eyelid opening following long‐term neuroleptic treatment of more than 6–8 years. Tardive dyskinesia and dystonia apart from the face were not found in either case. The symptoms fluctuated in their severities on a daily basis and were easily aggravated by various stimuli, e.g., stress, walking, reading and watching television. Electromyographic studies of their faces clearly indicated that the symptoms resulted from spontaneous blepharospasm and were analogous to idiopathic Meige's syndrome. Therefore, the patients’ difficulties in opening their eyes were considered to be the so‐called drug‐induced Meige's syndrome and/or facial tardive dystonia. It must be stressed that this syndrome is extremely distressing to patients and is a severe complication accompanying a long‐term neuroleptic treatment.