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Clinical Studies of Schizophrenia‐Like State in Epileptic Patients
Author(s) -
Kido Hideki,
Yamaguchi Nariyoshi
Publication year - 1989
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/j.1440-1819.1989.tb02940.x
Subject(s) - psychology , psychosis , epilepsy , schizophrenia (object oriented programming) , electroencephalography , audiology , psychiatry , neuroscience , medicine
Six subjects who suffered from epileptic seizures followed by a schizophrenia‐like state were examined. The mean duration between the onset of seizures and the psychotic state was 13.5 ± 6.6 years (mean ± S.D.). Five female subjects had episodic psychotic states and one man had a persistent one. Four subjects had localized temporal EEG abnormalities and the EEGs during psychotic states were different in each subject. During the psychotic state, no seizure was seen in the four subjects, a dierent seiznre frequency in the episodic case and an unchanged frequency in the persistent case. The psychotic features were characterized by K. Schneider's first‐rank symptoms. In order to understand the mechanisms of psychotic states, it will be useful to take into consideration the excitatory and inhibitory effects of neurotransmitters on limbic discharges.