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Tuberous Sclerosis and Partial Epilepsy
Author(s) -
Fukushima Katsuyuki,
Okabe Minora,
Muranaka Hideki,
Ohtani Kazumasa,
Morikawa Tateki,
Yagi Kazuichi,
Seino Masakazu
Publication year - 1987
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/j.1440-1819.1987.tb01757.x
Subject(s) - tuberous sclerosis , epilepsy , partial epilepsy , pediatrics , partial seizures , adaptability , epileptic seizure , complex partial seizures , medicine , psychology , age of onset , psychiatry , disease , biology , temporal lobe , ecology
Summary Partial epilepsy associated with tuberous sclerosis began at earlier ages and no epileptic seizure started after 15 years of age. According to the seizure manifestations at the onset, partial epilepsy was classified into 4 groups (I, C, NC and P Groups). The I Group manifested itself by 12 months. Partial seizure appeared between 4 and 7 years of age after the control of infantile spasms. The seizure prognosis and social adaptability of those cases were not necessarily unfavorable. In the C Group, the seizure started by 3 years of age and evolved into partial seizure with unsatisfactory prognosis and social adaptability. In the NC Group, the seizure developed by 2 years of age and the seizure type was modified in the time course. The seizure prognosis and social adaptability tended to be comparatively favorable. In the P Group, the seizure started after 4 years of age without an evolutionary modification of the seizure type. The seizure prognosis and social adaptability seemed to be satisfactory. The evolution of the seizure types was observed in all but the P Group, which occurred in the period between 4 and 7 years of age. The cases showing these evolutions amounted to 75% of partial epilepsy accompanying tuberous sclerosis, particularly 25% of which began with West syndrome.