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Epileptic Convulsion in Chimera Mice
Author(s) -
Fueta Yukiko,
Mita Takashi,
Matsuoka Shigeaki
Publication year - 1987
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/j.1440-1819.1987.tb01703.x
Subject(s) - chimera (genetics) , convulsion , white coat , coat , embryo , biology , anatomy , microbiology and biotechnology , genetics , neuroscience , epilepsy , endocrinology , gene , ecology , blood pressure
Summary Using a method of aggregation of embryos from the Fl progenies of ddY X El and ddY X C57BL/6J, seven chimera mice were produced. These seven chimera mice manifested various distributions of the white coat color derived from the Fl progeny of ddY X El. It was found that the chimera mouse, which had a larger percent of the white coat color, had a higher susceptibility to epileptic convulsion, the susceptibility having been proportional to the degree of the tissue mosaicism.