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Brain Stem Gliosis in a Case With Clinical Manifestations of Amyotrophic Lateral Sclerosis
Author(s) -
Takahata Naohiko,
Yamanouchi Toshio,
Fukatsu Ryo,
Katagiri Mizuho
Publication year - 1976
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/j.1440-1819.1976.tb00109.x
Subject(s) - gliosis , amyotrophic lateral sclerosis , pathological , pathology , medicine , paresis , pathogenesis , spinal cord , neuroscience , anatomy , biology , disease , surgery , psychiatry
Summary A 32‐year‐old male with typical clinical course of progressive bulbar paresis was investigated histopathologically. The main pathological change was prominent fibrous gliosis in the brain stem and cervical cord without remarkable nerve cell loss in the same area. Concerning the pathogenesis of this case, the significance of primary role of fibrous gliosis was discussed.