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Ultrastructure of Intracisternally Accumulated Dense Particles Observed in Nerve Cells of Rat Cerebellar Nuclei
Author(s) -
Takeichi Masashi
Publication year - 1975
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/j.1440-1819.1975.tb02322.x
Subject(s) - uranyl acetate , ultrastructure , endoplasmic reticulum , glycogen , uranyl , electron microscope , chemistry , pathology , staining , biophysics , biology , anatomy , biochemistry , physics , medicine , ion , organic chemistry , optics
Peculiar dense particles were accumulated within smooth-surfaced cisternae of some neuronal perilarya of cerebellar nuclei in rat. The particles were 200-450 A in size and spheroidal or slightly irregular in outline. They were low in contrast after uranyl acetate treatment, whereas they showed increase in electron density after uranyl and lead staining. Wigh respect to the possible nature of these intracisternal dense particles, the following interpretation was discussed. The particles concerned were probably identified as glycogen which had been synthetized by the agranular endoplasmic reticulum as an unusual cytological event.