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Non‐effective Group with L‐DOPA on Parkinsonism
Author(s) -
IZUMI Kanji,
INOUE Naohide,
KUROIWA Yoshigoro
Publication year - 1971
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/j.1440-1819.1971.tb01486.x
Subject(s) - parkinsonism , olivopontocerebellar atrophy , atrophy , medicine , anesthesia , central nervous system disease , degenerative disease , disease
Summary (L‐DOPA was supplied from Kyowa Hakko Co., Ltd. and from Dai‐Ichi Pharmaceutical Co., Ltd.) An effectiveness of L‐DOPA on 41 cases; 39 with idiopathic parkinsonism and 2 with olivopontocerebellar atrophy with parkinsonism, was observed. A comparison was made on several factors between 10 markedly and 9 non‐effective cases. It was found that there is a relationship between the effectiveness of L‐DOPA and an appearance of pyramidal signs which observed in all non‐effective whereas only in two out of 10 markedly effective cases. Discussions were made on the idiopathic parkinsonisms which accompany pyramidal signs and are refractive to L‐DOPA.