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EFFECTS ON SUBCORTICAL EEG, RECRUITING RESPONSES AND EEG AROUSAL OF CATS BY INTRAVENOUS INJECTION OF AMMONIUM BICARBONATE
Author(s) -
Wakabayashi Yutaka
Publication year - 1960
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/j.1440-1819.1960.tb02245.x
Subject(s) - electroencephalography , coma (optics) , reticular formation , cats , arousal , bicarbonate , anesthesia , chemistry , efferent , psychology , ammonium bicarbonate , neuroscience , stimulation , medicine , afferent , physics , organic chemistry , optics , raw material
Summary1 The typical synchronous triphasic wave in the case of hepatic coma was not recognized in this experiment. 2 1 to 2 cc solution of 2/3 mol ammonium bicarbonate, similar in the case of anoxia, diminished or abolished electrocortical activity, recruiting responses as well as EEG arousal. 3 The hypersynchronous discharges which were confined only to the reticular formation, excluding neo‐, archi‐, paleocortex and thalamus, were found concurrently with the activation in the spinal cord. The above two reactions were discovered to be potentiated with a small amount of strychine in the cases of both ammonia and anoxia. 4 Ammonium bicarbonate had a lowering effect on the brain activity in the case of intravenous injection. It is assumed that ammonia has generally a lowering effect on the activity levels of the brain.