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SOLUBLE PROTEIN FRACTION OF THE BRAIN TISSUE IN RELATION TO MATURATION OF THE BRAIN
Author(s) -
Kiyota Kazutami
Publication year - 1959
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/j.1440-1819.1959.tb02417.x
Subject(s) - brain tissue , chemistry , brain chemistry , biochemistry , electrophoresis , fraction (chemistry) , chromatography , biology , endocrinology , anatomy
SUMMARY1) Soluble protein in the cerebral hemisphere of the immature dog brains occupies fairly large proportion of the solid components, and it gradually decreases with growth of the brain, while, insoluble protein shows concomitant increase with active myelination in development. 2) Electrophoretic fractions of the soluble brain protein shows a variation with age. The more mature the brain tissue, the lower became the amounts of the soluble protein fractions with high hydration. This may likely account for the decrease of the hydrophilic property of brain tissue with added age. 3) Electrophoretic protein fractions of immature brain behave somewhat different from those of mature brain in precipitability through sodium sulfate and in coagulability through heat.