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INFLUENCE OF ELECTRICAL STIMULATION OF HYPOTHALAMUS UPON ELECTRICAL ACTIVITY OF CEREBRAL CORTEX IN CAT
Author(s) -
Nakagawa Isao
Publication year - 1958
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/j.1440-1819.1958.tb00740.x
Subject(s) - hypothalamus , thalamus , stimulation , neuroscience , cortex (anatomy) , cerebral cortex , cats , biology , medicine
Summary This author investigated the responses observable in the cerebral cortex and thalamus in case of the electrical stimulation of the hypothalamus of cats and could obtain the following results. 1. The single stimulation of the hypothalamus evoked afterdischarge in the diffuse areas of the cerebral cortex, whose pattern was much similar to the dial burst, thereby lacking of evoked potential, whereas high frequency stimulation of the hypothalamus caused the desynchronization of the diffuse thalamic projection system together with the desynchronization of the diffuse cortical areas. 2. The locus of the hypothalamus bringing about such effects lay in the dorsal hypothalamic area, Nucl. hypothalamicus lateralis, Nucl. hypothalamicus posterior, Nucl. supramammillaris, Nucl. interstitialis supramammillaris and decussatio supramammillaris, all situated at the postodorsal portion of the hypothalamus. 3. The high frequency stimulation of the hypothalamus effected upon the cortical strychinine spikes an increase both in amplitude and frequency. This effect was kept continued so long as the basic activities of the cortex went on desynchronizing, while it was found extinguished through sub‐cortical severance.