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A STUDY ON SCHIZOPHRENIA PART II. ON THE BLOOD GAS IN SCHIZOPHRENIA
Author(s) -
Kôsaka Mutsutoshi
Publication year - 1953
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/j.1440-1819.1953.tb01271.x
Subject(s) - schizophrenia (object oriented programming) , conviction , test (biology) , psychology , statistics , mathematics , psychiatry , law , paleontology , political science , biology
Summary 1. 523 blood gas tests treating 433 cases inclusive of normal subjects were undertaken. With a detailed investigation on the varied condition, I sorted under strict selection 157 cases of purely schizophrsnic process out of 433 cases mentioned, a number by far greater than Hayashi‘ 3 cases. A minute preparation of the preliminary conditions its well as perfection in manipulation moduawere also considered. In particular, improvement on the plotting method of the CO 2 absorption curve enabling me to accomplish a detailed observation under natural conditions was achieved. As the result, there were brought about refined qualification in the form, height, tension of the curve, variance in tension and pH, thus leading to attainment of values pretty different in Hayashi's essay. 2 According to Hayashli , the rate of the diagnotic possibility concerning schizophrenia was 46.7% by his single test method and 94.4 by the consecutive test method, whereas the rate of positive diagnotic possiblity by the present method, in principle also representing Haynshli's “single test method,” was able to return a value reaching as high as 98.8%. So it can be maintained with much conviction that these changes in the blood gas is quite intimatsly connected with schizophrenic mechanism, representing in themselves an esszntial phemmena inherent to the diseaso. 3. The result of the examination permits me to summarize briefly: the respiratory function in the cerebral blood reveals a decline in the acute stage owing to loss in the reserve alkali, becomes improved with increase of R. Q. in the chronic stage, due partly to increase of CO 2 output and partly due to decrease of CO 2 consumption. Each corresponding to the 3 clinical stages, average values of CO 2 output reads: 4 3–5.1–5.4 vol% against those of O 2 consume 5.7–5.3–5.1 vol%, consequently making a ratio of 0.75–0.95–1.05. 4. Concerning Hayashi's “ high valued aggravating type” with high balancing absorption curve and high percentage of CO 1 contents. I might enter into discussion hopingly in my later reports.