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CHANGES OF ELECTROENCEPHALOGRAM FOLLOWING ACETYLCHOLINE INJECTION INTO HYPOTHALAMUS OF CAT
Author(s) -
Nakao Hiroyuki
Publication year - 1953
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/j.1440-1819.1953.tb00605.x
Subject(s) - hypothalamus , acetylcholine , cats , cerebral cortex , cortex (anatomy) , neuroscience , chemistry , medicine , endocrinology , biology
Summary The electrical activity of the cerebral cortex and hypothalamus following the injection of ACH into the hypothalamus has been studied in anesthetized and non‐anesthetized cats. 1) Marked and manifold changes of electrical activity appear in the hypothalamus and the cerebral cortex synchronously after injection of the drug. In most cases, the train of regular slow or sharp waves which is changing gradually in its frequency is observed while the train recurs several times. Sometimes grand‐mal‐like discharge, diphasic spike, spike and dome discharge and the disappearance of waves are induced. 2) Among them, it is worthy of note that the latter two types of activity accompanied by specific outward demeanors of the cat each characteristic to the type. 3) It is suggested that the ACH‐discharge propagating from the hypothalamus and reaching the widespread cortical areas is mediated by the diffuse thalamic projection system.