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Relationship between the course of depression symptoms and the left ventricular mass index and left ventricular filling pressure in chronic haemodialysis patients
Author(s) -
KIM YONG KYUN,
PARK CHAN S,
IHM SANGHYUN,
KIM HEEYEOL,
HONG TAI Y,
KIM DAI J,
PAE CHIUN,
SONG HO C,
KIM YONGSOO,
CHOI EUY J
Publication year - 2011
Publication title -
nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.752
H-Index - 61
eISSN - 1440-1797
pISSN - 1320-5358
DOI - 10.1111/j.1440-1797.2010.01372.x
Subject(s) - medicine , depression (economics) , left ventricular hypertrophy , cardiology , blood pressure , body mass index , st depression , st segment , myocardial infarction , economics , macroeconomics
Aim: Multiple measurements of depression symptoms over time were more predictive of cardiovascular mortality than a single time measurement performed at baseline. The aim of this study is to evaluate the association of the course of depression symptoms, based on repeated assessments of depression symptoms over time, with left ventricular mass index (LVMI) and left ventricular filling pressure (LVFP) in patients on haemodialysis (HD). Methods: The level of depression symptoms in 61 patients on HD were prospectively assessed using the Beck Depression Inventory (BDI) at baseline and at three intervals (5, 10, 15 months). Doppler echocardiographic examinations were performed at the end of follow up. Results: At the end of follow up, the patients were divided into three groups according to their course of depression symptoms: non‐depression ( n = 21), intermittent depression ( n = 23) and persistent depression ( n = 17). LVMI and LVFP were significantly increased in the persistent depression symptoms group compared to those of the non‐depression symptoms group and the intermittent depression symptoms group. Persistent depression symptoms were independently associated with LVMI (β‐coefficient = 0.347, P = 0.017) and LVFP (β‐coefficient = 0.274, P = 0.048) after adjustment for age, sex, systolic blood pressure, diastolic blood pressure, diabetes and interdialytic weight gain. Conclusion: In our study, persistent depression symptoms were associated with left ventricular hypertrophy and diastolic dysfunction. Our data may provide a more complete understanding of cardiovascular risk associated with depression symptoms in patients on HD.