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Crystalloid deposits in the kidney
Author(s) -
KELLER LISA SUZANNE,
FAULL RANDALL JAMES,
SMITH PETER,
SWIFT JEFFREY,
BANNISTER KYM MALCOLM,
OTTO SOPHIE,
PEH CHEN AU
Publication year - 2005
Publication title -
nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.752
H-Index - 61
eISSN - 1440-1797
pISSN - 1320-5358
DOI - 10.1111/j.1440-1797.2005.00290.x
Subject(s) - medicine , multiple myeloma , renal biopsy , lymphoproliferative disorders , biopsy , nephropathy , bone marrow , differential diagnosis , kidney , pathology , immunoglobulin light chain , lymphoma , immunology , endocrinology , antibody , diabetes mellitus
SUMMARY: Light chain‐producing lymphoproliferative disorders such as multiple myeloma are frequently complicated by renal impairment. Typically, the renal biopsy of a patient with renal failure caused by multiple myeloma shows cast nephropathy, but occasionally crystals may be seen. We describe the case of a patient with acute renal failure caused by multiple myeloma in which, on renal and bone marrow biopsy, there were widespread crystalloid deposits. Crystalloid nephropathy is a very rare condition associated with multiple myeloma and other light chain‐secreting disorders. An underlying lymphoproliferative disorder should be considered in the differential diagnosis if crystalloid deposits are seen on a renal or other tissue biopsy.