Premium
Differentiating paroxysmal nocturnal haemoglobinuria and pre‐eclampsia in pregnancy
Author(s) -
BROWN MA,
MCMAHON L
Publication year - 2002
Publication title -
nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.752
H-Index - 61
eISSN - 1440-1797
pISSN - 1320-5358
DOI - 10.1111/j.1440-1797.2002.tb00496.x
Subject(s) - medicine , gestation , pregnancy , eclampsia , preeclampsia , presentation (obstetrics) , obstetrics , fetus , twin pregnancy , in utero , genetics , biology
SUMMARY: During her first pregnancy, a 26‐year‐old‐woman developed symptoms of severe preeclampsia at 23 weeks gestation. Fetal death in utero was confirmed shortly after presentation. A similar event at 13 weeks gestation in her second pregnancy prompted further investigation. She was found to have a rare form of haemolytic anaemia, paroxysmal nocturnal haemoglobinuria (PNH). Supportive management with prednisolone and anticoagulation enabled the gestation to continue and she was delivered successfully at 34 weeks.